Generally speaking, GMP (good manufacturing practices) cleanrooms are treated with a sporicidal agent on a recurring basis. Typical sporicidal products have hydrogen peroxide, peroxyacetic acid and acetic acid as their active ingredients. These products are corrosive to the eyes and skin in their concentrated form. Even when diluted, they still can be very irritating. Additionally, their vapors can cause respiratory irritation, especially in sensitive individuals. Dripping, spraying, and splashing solutions present contact risks, while aerosols and vapors present inhalation risks. There are occupational exposure limits for all three active ingredients. Application procedures typically involve wet mopping or spray application on the relevant surfaces, including ceilings, walls, floors, and, in some cases, cleanroom equipment. In addition to donning standard cleanroom garments, the typical ensemble may include use of a cartridge or powered respirator. Eye protection should also be worn. Avoid heavy exposures to solutions that could soak through cleanroom garments and contact the wearer’s skin. Certain situations may warrant higher-level chemical-resistant garments.
The products below are examples of garments in the DuPont portfolio that might be suitable for use in Example One:
Tyvek® 800J | Tyvek® IsoClean® Coverall